Black Cohosh Hepatic Safety: Follow-Up of 107 Patients Consuming a Special Cimicifuga racemosa rhizome Herbal Extract and Review of Literature

Table 2

Follow up of patients assuming Cimicifuga.

Parameter	Values
Physical examination
BMI	28.5 (SD 0.71)
Blood pressure
systolic	125 (SD 7.07)
diastolic	75 (SD 21.21)
Heart rate	76.5 (SD 0.71)
Few patients (9/107) were suffering of minor complaints, that revalued after 1 month did not show any sign of liver disease
Abdominal pain	5 (4.6%)
Paresthesias	3 (2.8%)
Fatigue	2 (1.8%)
Anorexia	1 (0.9%)
Myalgia	1 (0.9%)
Malaise	1 (0.9%)
Pruritus	1 (0.9%)
Fever	0
Skin rash	0
Jaundice	0
Laboratory findings
Leukocyte total count	4250 mm^3 (SD 1060)
Bilirubin	0.75 mg dl^−1 (SD 0.07)
AST	29.5 IU^−1 (SD 10.61)
ALT	15.5 IU l^−1 (SD 17.68)
Alkaline Phosphatase	135 U l^−1 (SD 63.64)
GGT	28 U l^−1 (SD 7.07)
Albumin	3.75 g dl^−1 (SD 0.49)
INR	1 (SD 0.14)