Original Article

Phytomedicinal Role of Pithecellobium dulce against CCl4-mediated Hepatic Oxidative Impairments and Necrotic Cell Death

Figure 2

Dose dependent effect of AEPD on ALT activity against CCl4-induced hepato-toxicity. Vehicle: ALT activity in normal mice, CCl4: ALT activity in CCl4-treated mice, AEPD-25, AEPD-50, AEPD-75, AEPD-100, AEPD-150, AEPD-200, AEPD-250, AEPD-300: ALT activity in AEPD-treated mice for 7 days at a dose of 25, 50, 75, 100, 150, 200, 250 and 300 mg kg−1 body weight prior to CCl4 intoxication. Data are mean ± SD, for six animals per group and were analyzed by one-way ANOVA, with Student-Newman-Keuls post hoc tests. Differences were attributed at P < .05, and homogeneous subgroups share common superscripted letters.
832805.fig.002