Influence of Oreocnide integrifolia (Gaud.) Miq on IRS-1, Akt and Glut-4 in Fat-Fed C57BL/6J Type 2 Diabetes Mouse Model

Table 1

Body weight and food intake.

	Control	Diabetic	OI extract treated
Body weight initial (g)	24.2 ± 0.23	23.7 ± 0.41^ns	22.6 ± 0.78^ns/ns
Body weight final (g)	26.1 ± 0.43	41.3 ± 1.81***	29.3 ± 0.48^ns/♦♦♦
Weight gain (g)	1.9 ± 0.37	17.6 ± 0.67***	6.7 ± 0.32^***/♦♦♦
Food intake (g day^-1 per mouse)	2.6 ± 0.17	1.87 ± 0.13*	2.2 ± 0.18^ns/ns

Effect of OI extract on body weight and food intake in control and experimental animals. Mean ± SEM of six animals.
^{***/♦♦♦}P < .001, *P < .05, ns = P > .05; where * = control versus diabetic, control versus OI extract-treated and ♦ = diabetic versus OI extract-treated.