KIOM-4 Protects against Oxidative Stress-Induced Mitochondrial Damage in Pancreatic β-cells via Its Antioxidant Effects
Figure 6
The effect of KIOM-4 on intracellular ATP level, mitochondrial enzyme, and insulin level. (a) ATP content was assayed using a luciferase/luciferin ATP determination kit. (b) Mitochondrial succinate dehydrogenase activity was estimated by the MTT assay. (c) The amount of insulin was determined by using an ELISA rat specific insulin enzyme immunoassay kit. Asterisk represent significantly different from control cells (P < .05) and double asterisk represent significantly different from STZ-treated cells (P < .05).
