Original Article

Inhibition of Anchorage-Independent Proliferation and G0/G1 Cell-Cycle Regulation in Human Colorectal Carcinoma Cells by 4,7-Dimethoxy-5-Methyl-l,3-Benzodioxole Isolated from the Fruiting Body of Antrodia camphorate

Figure 7

Schematic diagram of signaling pathways involved in SY-1-induced cell-cycle arrest and apoptosis in human COLO 205 cells. SY-1 was isolated from the fruiting body of AC (upper left). After treatment with SY-1, the p53-regulated p21/p27 signals in COLO 205 cells resulted in inhibition of soft agar colony formation.
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