Antiproliferative and Proapoptotic Effects of <i>Labisia pumila</i> Ethanol Extract and Its Active Fraction in Human Melanoma HM3KO Cells

<table>Induction of apoptosis in HM3KO cells by SF2Lp at the IC<sub>50</sub> concentration (7.59 <i>μ</i>g/mL) at different exposure times (24, 48, and 72 h) as detected by AO-EB double staining. *<svg height="11.375" id="M37" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> was taken as significantly different from control. Each value represents means ± SD from three independent experiments. SF2Lp-induced HM3KO cell death via apoptosis increased significantly in a time-dependent manner as compared to control.</table>

Evidence-Based Complementary and Alternative Medicine

fig4

Figure 4

Figure 4: Antiproliferative and Proapoptotic Effects of <i>Labisia pumila</i> Ethanol Extract and Its Active Fraction in Human Melanoma HM3KO Cells 

Evidence-Based Complementary and Alternative Medicine

Antiproliferative and Proapoptotic Effects of Labisia pumila Ethanol Extract and Its Active Fraction in Human Melanoma HM3KO Cells

Figure 4