Isolation of Antidiabetic Principle from Fruit Rinds of Punica granatum

Table 2

Effect of MEPG and VAD isolated from fruit rinds of Punica granatum on aldose reductase enzyme activity in in vitro.

Sl. no	Sample	Concentration (μg/mL)	% Inhibition^#	IC50 (μg/mL)^*
		0.3	22.95±0.25
		0.6	35.38±0.47
(1)	Methanolic extract	1.2	45.77±0.14	2.050
		2.5	65.64±0.74
		5	84.49±0.21
		10	99.62±0.33
		0.15	9.31±0.84
		0.3	26.63±0.18
(2)	Valoneic acid dilactone	0.6	48.50±0.54	0.788
		1.2	67.80±0.71
		2.5	79.19±0.21
		5	89.43±0.34
		0.5	8.03±0.62
(3)	Quercetin	1.0	24.23±0.51	2.807
		2.0	42.48±0.91
		5.0	82.45±0.27

Values are expressed as mean ± SEM (% inhibition^#) and mean (IC^∗₅₀) of three trials.