Treatment of Common Cold Patients with the Shi-Cha Capsule: A Multicenter, Double-Blind, Randomized, Placebo-Controlled, Dose-Escalation Trial

Table 4

Intent-to-treat and per-protocol analyses of main symptom score, minor symptom score, and cumulative symptom score.

Intent-to-treat analysis	Change from baseline to day 4 (mean ± SD)
	Group A (n = 114)	Group B (n = 117)	Group C (n = 115)
Main symptom score	8.842 ± 3.453	8.513 ± 3.050	7.330 ± 4.209
P value versus group C	<0.0001	<0.0001
Minor symptom score	5.851 ± 2.839	6.120 ± 2.443	5.157 ± 2.648
P value versus group C	<0.0001	<0.0001
Cumulative symptom score	14.320 ± 5.577	13.890 ± 4.949	11.920 ± 6.090
P value versus group C	<0.0001	<0.0001
Per-protocol analysis	Group A (n = 113)	Group B (n = 113)	Group C (n = 108)
Main symptom score	8.920 ± 3.365	8.522 ± 3.094	7.417 ± 4.212
P value versus group C	<0.0001	<0.0001
Minor symptom score	5.876 ± 2.838	6.053 ± 2.394	5.241 ± 2.696
P value versus group C	<0.0001	<0.0001
Cumulative symptom score	14.420 ± 5.498	13.850 ± 5.016	12.060 ± 6.143
P value versus group C	<0.0001	<0.0001