Momordica charantia Extract Induces Apoptosis in Human Cancer Cells through Caspase- and Mitochondria-Dependent Pathways

Figure 1

Inhibitory effect of MCME on the viability of cancer cells. Hone-1, AGS, HCT-116, and CL1-0 cells were used to evaluate the anticancer activity of MCME. Cell viability was determined by dose-response curves obtained by the MTT assay. To comparatively evaluate the susceptibility of cells to MCME, data of each cell line were shown only at concentrations ranging from 0.15 to 0.35 mg/mL for the approximate viability of 75% and 50% at 24 h for each. All experiments were performed in triplicate, and results are expressed as mean ± SD at a sample number of 8 for each experiment. (*) and (**) indicate significant 𝑃 values <0.05 and <0.01, respectively, as compared to control (Ctrl).