Beneficial Effect of Shikonin on Experimental Colitis Induced by Dextran Sulfate Sodium in Balb/C Mice

Figure 8

Expression of proinflammatory genes in peritoneal macrophages isolated from Balb/C mice. Proinflammatory gene expression levels were measured using RT-PCR, as described in Section 2. Representative photographs from ten independent experiments with each gene are shown. β-Actin served as the internal control. The expression seen in the lipopolysaccharide-stimulated group (control) was standardized as 100% expression. ^∗𝑃<0.05, ^∗∗𝑃<0.01; significantly different from the control group; ^#𝑃<0.05, ^##𝑃<0.01; significantly different from the blank (unstimulated) group, determined by means of a one-way analysis of variance followed by Dunnett’s t-test (𝑛=10).

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