Beneficial Effect of Shikonin on Experimental Colitis Induced by Dextran Sulfate Sodium in Balb/C Mice

Table 2

Histologic scoring system for DSS-induced colitis.

Scoring of severity of histological damage
Feature	Score	Description
Severity of inflammation	0	None
	1	Mild
	2	Moderate
	3	Severe
Extent of inflammation	0	None
	1	Mucosa
	2	Mucosa and submucosa
	3	Transmural
Crypt damage	0	None
	1	1/3 damaged
	2	2/3 damaged
	3	Crypts lost, surface epithelium present
	4	Crypts lost and surface epithelium lost

^**Scores were calculated by adding the score for the three parameters, giving a maximum score of 10.