Ethanol Extracts of Fruiting Bodies of Antrodia cinnamomea Suppress CL1-5 Human Lung Adenocarcinoma Cells Migration by Inhibiting Matrix Metalloproteinase-2/9 through ERK, JNK, p38, and PI3K/Akt Signaling Pathways
Figure 4
Effects of EEAC on MMP-2 and MMP-9 activities of CL1-5 cells. (a) Cells were treated with various concentrations (0.125, 0.25, 0.5, and 1.0 μg/mL) of EEAC for 36 h. The conditioned media were collected, and MMP-2, and MMP-9 activities were determined by gelatin zymography. (b) The activities of these proteins were subsequently quantified by densitometric analysis. Values (means ± SD, ) differ significantly () (lower case for MMP-2 and upper case for MMP-9).
