Research Article

Ethanol Extracts of Fruiting Bodies of Antrodia cinnamomea Suppress CL1-5 Human Lung Adenocarcinoma Cells Migration by Inhibiting Matrix Metalloproteinase-2/9 through ERK, JNK, p38, and PI3K/Akt Signaling Pathways

Figure 8

Proposed signaling pathways for EEAC-mediated inhibition against migration of CL1-5 cells. The effect of EEAC is achieved likely through the inhibition of FAK, which regulates Rac-1/MMP-9 expression through MAPK and PI3K/AKT signaling pathways.
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