Ixora parviflora Protects against UVB-Induced Photoaging by Inhibiting the Expression of MMPs, MAP Kinases, and COX-2 and by Promoting Type I Procollagen Synthesis

Figure 9

Effect of Ixora parviflora extract on NO production in human fibroblasts (a) and the UV-induced expression of COX-2 (b). Human fibroblasts (Hs68) were treated with/without UV 40 mJ/cm² and Ixora parviflora extract (IPE) of 1, 5, 10, and 50 𝜇g/mL. (𝑛=3; Significant difference versus control (non-UV-exposed): ^∗∗∗𝑃<0.001. significant inhibition versus UV-exposed group: ^#𝑃<0.05; ^##𝑃<0.01; ^###𝑃<0.001; EGCG: (−)-epigallocatechin gallate.).

(a)

(b)