Evidence-Based Complementary and Alternative Medicine / 2012 / Article / Tab 1 / Research Article
Involvement of the Cerebral Monoamine Neurotransmitters System in Antidepressant-Like Effects of a Chinese Herbal Decoction, Baihe Dihuang Tang, in Mice Model Table 1 The effect of BDT on the monoamine neurotransmitter levels and 5-HIAA/5-HT turnover ratio in brain after mouse TST.
Group Dose Ratio of brain/body (%) Monoamine neurotransmitter level (μ g/g wet tissue)
5-HIAA/5-HT NA DA 5-HT 5-HIAA Normal —
1
.
1
6
±
0
.
0
2
4
1
.
0
8
±
0
.
0
4
1
.
2
1
±
0
.
0
5
1
.
4
9
±
0
.
0
4
0
.
4
8
±
0
.
0
5
0
.
3
2
±
0
.
0
3
Vehicle —
1
.
1
9
±
0
.
0
3
1
0
.
7
7
±
0
.
0
7
#
#
0
.
9
7
±
0
.
0
9
1
.
0
7
±
0
.
1
5
#
#
0
.
3
5
±
0
.
0
7
0
.
3
2
±
0
.
0
2
Desipramine (mg/kg)
20
1
.
2
5
±
0
.
0
5
6
1
.
1
5
±
0
.
0
3
∗
∗
1
.
0
1
±
0
.
0
3
1
.
8
7
±
0
.
0
5
∗
∗
0
.
5
5
±
0
.
0
3
0
.
2
9
±
0
.
0
1
BDT (g/kg)
4.5
1
.
1
8
±
0
.
0
2
5
0
.
7
8
±
0
.
0
8
1
.
0
4
±
0
.
0
2
1
.
2
3
±
0
.
1
3
0
.
3
9
±
0
.
0
9
0
.
3
1
±
0
.
0
5
9.0
1
.
2
6
±
0
.
0
7
1
0
.
7
9
±
0
.
0
7
1
.
0
1
±
0
.
0
5
1
.
4
8
±
0
.
1
1
∗
0
.
4
2
±
0
.
0
5
0
.
2
8
±
0
.
0
6
18.0
1
.
2
1
±
0
.
0
5
3
0
.
9
1
±
0
.
0
6
∗
1
.
0
2
±
0
.
0
7
1
.
7
4
±
0
.
0
6
∗
∗
0
.
5
1
±
0
.
0
4
∗
0
.
2
5
±
0
.
0
2
∗
Values were expressed as mean
±
SEM (
𝑛
=
1
0
).
#
#
𝑃
<
0
.
0
1
as compared with the normal group.
∗
𝑃
<
0
.
0
5
and
∗
∗
𝑃
<
0
.
0
1
as compared with the vehicle group.
