Differential Association of Uncoupling Protein 2 Polymorphisms with Pattern Identification among Korean Stroke Patients: A Diagnostic System in Traditional Korean Medicine
Table 1
Clinical differences among the pattern identification groups of Korean stroke patients.
Characteristics
Control
Qi deficiency
value
Dampness & Phlegm
value
Yin deficiency
value
Fire & Heat
value
588
397
645
223
521
Anthropometric characteristics
Sex (M/F)
273/314*
135/262
<.0001
314/331
0.445
97/126
0.4424
387/135
<.0001
Age (year)
64 (58, 69)#
69 (60, 77)
<.0001
69 (61, 75)
<.0001
73 (65, 79)
<.0001
68 (59, 75)
<.0001
Smoking (none/stop/active)
299/232/56
278/51/68
<.0001
396/95/153
<.0001
144/46/33
<.0001
202/129/191
<.0001
Drinking (none/stop/active)
357/35/195
260/37/100
0.0084
381/66/196
0.021
137/25/61
0.0205
186/81/255
<.0001
Weight (kg)
62.0 (56.0, 69.0)
56.6 (50.0, 62.8)
<.0001
70.0 (63.0, 78.0)
0.046
56.1 (50.0, 64.0)
<.0001
65.0 (57.0, 72.0)
0.0012
BMI (kg/m2)
24.2 (22.6, 26.0)
22.6 (20.9, 24.4)
<.0001
24.6 (22.5, 26.7)
0.059
22.5 (20.5, 24.7)
<.0001
24.0 (22.0, 26.1)
0.12
Waist circumference (cm)
85.0 (79.3, 90.0)
85.0 (79.0, 91.0)
0.436
89.0 (82.0, 95.0)
<.0001
83.0 (76.0, 89.0)
0.042
88.0 (82.0, 94.0)
<.0001
WHR
0.88 (0.84, 0.91)
0.92 (0.88, 0.96)
<.0001
0.94 (0.90, 0.97)
<.0001
0.93 (0.89, 0.96)
<.0001
0.94 (0.90, 0.98)
<.0001
History
TIA (Yes)
15
30
0.0002
53
<.0001
26
<.0001
42
<.0001
Hypertension (Yes)
107
232
<.0001
416
<.0001
131
<.0001
325
<.0001
Hyperlipidemia (Yes)
70
50
0.7163
96
0.1242
19
0.1689
55
0.5114
Diabetes (Yes)
40
103
<.0001
187
<.0001
57
<.0001
143
<.0001
Heart disease (Yes)
0
23
<.0001
48
<.0001
14
<.0001
27
<.0001
Serum parameter
GOP (U/mL)
23.0 (20.0, 29.0)
22.0 (18.0, 28.0)
<.0001
23.0 (18.0, 28.1)
0.0005
22.0 (18.0, 28.0)
0.0009
23.0 (18.0, 31.0)
0.1316
GPT (U/mL)
21.0 (16.0, 30.0)
18.0 (13.0, 28.0)
<.0001
19.0 (14.0, 28.0)
<.0001
17.0 (13.0, 26.0)
<.0001
21.0 (15.0, 32.0)
0.4774
Total cholesterol (mg/dL)
199.0 (175.0, 226.0)
178.0 (154.0, 211.0)
<.0001
189.0 (160.0, 219.0)
<.0001
185.0 (159.0, 212.0)
<.0001
178.0 (148.0, 207.0)
<.0001
Triglyceride (mg/dL)
131.0 (91.0, 182.0)
121.0 (88.0, 175.6)
0.398
132.0 (94.0, 195.0)
0.1055
123.5 (83.0, 174.0)
0.2128
131.5 (93.0, 194.0)
0.3019
HDL-cholesterol (mg/dL)
51.0 (43.2, 59.9)
42.9 (35.9, 52.0)
<.0001
41.0 (33.5, 48.8)
<.0001
42.7 (35.1, 49.4)
<.0001
41.0 (34.0, 49.0)
<.0001
Blood sugar (mg/dL)
99.0 (92.0, 106.0)
101.5 (91.0, 130.0)
0.0023
107.0 (94.0, 128.0)
<.0001
107.0 (98.0, 141.0)
<.0001
105.0 (94.0, 128.5)
<.0001
*Indicates number of subjects, and #indicates value of median (25% and 75% interquartiles). The value of categorized variables was calculated by a chi-squared test or Fisher’s test, and continuous values were analyzed by a Mann-Whitney U test after a normality test and compared with the normal group.
