Anticancer Activity of Certain Herbs and Spices on the Cervical Epithelial Carcinoma (HeLa) Cell Line

Table 2

Summary of the IC₅₀ values and selectivity indexes of the plant extracts.

Plant extracts	HeLa IC50^a; (μg/mL) ± SD	Vero IC50; (μg/mL) ± SD	SI^b
Rosmarinus officinalis (McConnell’s Blue)	>100	12.03±0.02	0.12
Rosmarinus officinalis (Tuscan Blue)	23.31±0.055	23.64±0.10	0.52
Lavandula-x-intermedia (Margaret Roberts)	182±1.5	31.5±0.14	0.17
Lavandulaspica	98.99±1.28	26.3±0.64	0.27
Origanumvulgare	126.3±1.00	163.8±2.95	1.30
Petroselinumcrispum	172.7±0.25	105±0.50	0.61
Laurusnobilis	34.46±0.48	124.1±18.8	3.61
Thymusvulgaris	>200	138.4±2.60	0.66
Foeniculumvulgare	129.7±2.05	85.37±5.26	0.66
Capsicum annuum (Paprika)	>200	122.3±3.76	0.58
Actinomycin D^c	0.002	0.027	13.5

^aFifty percent inhibitory concentration.
^bSelectivity index.
^cPositive control for cytotoxicity assay.