Inhibitory Effects of Chung Hun Wha Dam Tang (CHWDT) on High-Fat Diet-Induced Obesity via AMP-Activated Protein Kinase Activation
Figure 2
CHWDT down regulates lipogenic gene SREBP1c and FAS expression in hepatocytes. HepG2 cells (a) and AML cells (b) were pretreated with CHWDT (50 and 100 g/mL) for 1 h and palmitate (0.45 mM) was used for 12 h and mRNA levels of SREBP1c and FAS were measured. SREBP1c and FAS mRNA levels were analyzed from liver tissue collected high fat diet induced obese mice (c) The representative bands are shown from at least three independent experiments.
