Angelicae Dahuricae Radix Inhibits Dust Mite Extract-Induced Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice

Figure 1

Severity scores and histological changes of treated backs and ears in NC/Nga mice. (a) Representative features and histological changes following consecutive administration of Angelicae Dahuricae Radix (AR) or tacrolimus to Dermatophagoides farinae-induced AD-like lesions on the back and ears. The images show the back and ears 4 weeks after sensitization. (b) Effect of consecutive administration of AR or tacrolimus on dermatitis score of D. farinae-induced AD-like lesions on the back and ears. AR or tacrolimus were administrated once daily for 4 weeks. (c) Histological features of AD-like lesions treated with AR. The dermatitis scores were evaluated by the procedures described in Materials and Methods (mean ± SEM (𝑛=5), *: 𝑃<0.05, compared with D. farinae-induced group).

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