Myricetin Increases Hepatic Peroxisome Proliferator-Activated Receptor α Protein Expression and Decreases Plasma Lipids and Adiposity in Rats
Figure 1
Effect of myricetin or fenofibrate on triglyceride (TG) content in 3T3-L1 adipocytes. (a) Microscopic (40x magnification) images of oil red O-stained adipocytes. Photomicrographs are of tissues isolated from vehicle-treated 3T3-L1 adipocytes (vehicle), myricetin- (0.001 μmol L−1) treated adipocytes (myricetin 0.001), myricetin- (0.01 μmol L−1) treated adipocytes (myricetin 0.01), myricetin- (0.1 μmol L−1) treated adipocytes (myricetin 0.1), myricetin (1.0 μmol L−1)-treated adipocytes (myricetin 1.0), or fenofibrate- (1.0 μmol L−1) treated adipocytes (fenofibrate 1.0). The vehicle (distilled water) used to dissolve the tested medications was given at the same volume. (b) Quantification of oil red O staining. The experiments were performed in at least 4 replicates per treatment. Values were expressed as mean with SEM ( per group) in each column. a and b compared to the values of vehicle-treated group.
