Regulation of Proinflammatory Mediators via NF-κB and p38 MAPK-Dependent Mechanisms in RAW 264.7 Macrophages by Polyphenol Components Isolated from Korea Lonicera japonica THUNB
Figure 6
Effect of polyphenols on phosphorylation of MAPKs in RAW 264.7 macrophages. RAW 264.7 cells were pretreated with the indicated concentrations of polyphenols for 1 h and treated with LPS (1 μg/mL) for 15 min. The cell lysates were analyzed by Western blot for the detections of phosphorylation of ERK1/2, JNK, and p38 MAPK. Data are the mean ± SD of triplicates. The asterisk (*) indicates a significant difference from the control group () and **indicates significant difference from the LPS-treated group ().
