Sphingosine Kinase-1-Dependent and -Independent Inhibitory Effects of Zanthoxyli Fructus to Attenuate the Activation of Mucosal Mast Cells and Ameliorate Food Allergies in Mice
Figure 3
The effect of ZF (0.32 mg/mL) on the mRNA expression levels of Sphk1. The sensitized mBMMCs were incubated with ZF or vehicle for 30 min and were stimulated with (filled) or without (open) DNP-BSA. The mRNA levels of Sphk1 were analyzed by real-time PCR. The results are expressed as the relative ratio to the vehicle-treated mBMMCs without DNP-BSA stimulation. The data are expressed as the mean ± SD (). # compared with DNP-BSA (−), * compared with the vehicle.
