Rhein Induces Apoptosis in Human Breast Cancer Cells

Figure 2

Effect of anthraquinone derivatives on the growth of human breast cancer cells. MCF-7/VEC (a) and MCF-7/HER2 (b) cells were plated in 96-well plates (5 × 10⁴ cells/well) and then treated with serial dilution of each tested compound. After treatment for 48 h, cell growth was examined using MTT assay. OD_570-630 in each well was measured with a micro-ELISA reader. Survival rate (%)=((A_control−A_experiment)/A_control)×100. *𝑃value<0.05; **𝑃value<0.01 compared with untreated cells.

(a)

(b)