Diosgenin Induces Apoptosis in HepG2 Cells through Generation of Reactive Oxygen Species and Mitochondrial Pathway

<table>Effects of diosgenin on caspases (a), Bcl-2 family proteins, and cytochrome <i>c</i> (b). Cells were incubated without or with 20 <i>μ</i>M, 30 <i>μ</i>M, and 40 <i>μ</i>M of diosgenin for 24 h. Total cell lysates were analyzed by immunoblotting with antibody against caspase-3 (pro and cleavage), procaspase-8, procaspase-9, PARP, Bcl-2, Bax, Bid, and cytochrom <i>c</i>.</table>

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Figure 3: Diosgenin Induces Apoptosis in HepG2 Cells through Generation of Reactive Oxygen Species and Mitochondrial Pathway 