Inhibitory Effects of Baicalin on the Expression and Activity of CYP3A Induce the Pharmacokinetic Changes of Midazolam in Rats
Figure 4
The increase in (a) and the decrease in CL (b) of MDZ (10 mg/kg, i.v.) after treatment with baicalin at a single dose of 0.225 g/kg () or 0.45 g/kg () or at a dose of 0.90 g/kg once for 1 day and the same dose for 7 days ().