Anti-Diabetic Activities of Jiaotaiwan in db/db Mice by Augmentation of AMPK Protein Activity and Upregulation of GLUT4 Expression
Figure 4
JTW ameliorates islet morphology in pancreas and β-cell function. (a) HE stain of pancreas sections, 200 (). (b) Images of pancreatic islet β cells under TEM, 6000x. The samples were prepared as described in Section 2, and pictures of the cells in the islet center were taken to observe β cell morphology by TEM; (black arrow)β-SGs, (white arrow)α-SGs (). (c) Immunohistochemical stain of insulin in pancreas sections, 200x (). (d) Pancreatic insulin content. After insulin immunohistochemical staining, the deeply stained insulin-positive cells in pancreatic islets were tested with an I-solution Image Analysis System (). Data are presented as the mean ± SE. *, ** versus the model control group.
