Qushi Huayu Decoction Inhibits Hepatic Lipid Accumulation by Activating AMP-Activated Protein Kinase In Vivo and In Vitro
Figure 8
QHD inhibits hepatic lipid accumulation by activating AMPK. QHD significantly stimulates AMPK phosphorylation, decreases nuclear SREBP-1 and ChREBP protein contents, down-regulates ACCα expression and up-regulates phosphorylation of ACCα, and then decreases hepatic de novo lipogenesis and accumulation.