Evidence-Based Complementary and Alternative Medicine

Review Article

What Is the de-qi-Related Pattern of BOLD Responses? A Review of Acupuncture Studies in fMRI

Table 3

mixed-related BOLD responses evoked by acupuncture stimulation.
Regions (References no.)
ActivationsDeactivations
Somatosensory system  
 SI[71, 75][75]
 SII[72, 75, 76] 
 thalamus[77][53]
 Supermarginal[76] 
 putamen[71][71]
 brainstem[77][77]
Motor system  
 M1[71, 75, 76][74]
 cerebellum[53, 72, 74] 
 SMA[75, 77] 
Sensory integration system  
 insula[53, 71, 75–77][71]
 ACC [77]
Special senses  
 IFG[75, 76] 
 STG[75][53, 71]
 MTG [53]
Frontal cortex  
 vmPFC [77]
 Frontal Pole [74]
 Frontal operculum[75] 
 Medial orbital prefrontal cortex [72]
 Medial frontal gyrus [74]
 DLPFC/VLPFC[75, 76][75]
 DMPFC[75] 
 Paracentral lobule [77]
 Amygdala[76][77]
 Hippocampus[76] 
 Parahippocampus[53] 
 Lentiform nucleus [71]
 PAG [76]
Temporal/parietal cortex  
 Inferior temporal gyrus [72, 74]
 Inferior parietal lobe[72][75]
 Precuneus [71, 74, 75, 77]
 Superior parietal lobule[75] 
 traisverse temporal gyrus[72] 
Occipital cortex  
 Lingual gyrus [53, 75]
 Cuneus[75] 
 Occipital gyrus [53, 72, 74]
 angular gyrus[75] 
 fusiform gyrus [53]
Cingulate gyrus  
 PCC [71, 75, 77]
 pMCC[76, 77]