Berberine Reduces the Metastasis of Chondrosarcoma by Modulating the αvβ3 Integrin and the PKCδ, c-Src, and AP-1 Signaling Pathways

Figure 3

Berberine inhibits expression of the αvβ3 integrin in chondrosarcoma cells. ((a)–(d)) Cells were incubated with various concentrations of berberine for 24 h; mRNA and cell surface expression of αvβ3 integrin were examined by qPCR and flow cytometry. Results are expressed as the mean ± S.E.M.*, 𝑃<0.05 compared with control.

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