Berberine Reduces the Metastasis of Chondrosarcoma by Modulating the αvβ3 Integrin and the PKCδ, c-Src, and AP-1 Signaling Pathways
Figure 4
PKCδ and c-Src signaling pathways are involved in the berberine response of human chondrosarcoma cells. ((a) and (b)) Cells were incubated with various concentrations of berberine for 24 h; PKCδ kinase activity was examined by use of the PKCδ kinase activity kit. ((c) and (d)) Cells were incubated with various concentrations of berberine for 24 h; c-Src kinase activity was examined by use of the c-Src kinase activity kit. Results are expressed as the mean ± S.E.M.*, compared with control.
