Berberine Reduces the Metastasis of Chondrosarcoma by Modulating the αvβ3 Integrin and the PKCδ, c-Src, and AP-1 Signaling Pathways
Figure 5
AP-1 mediates the response of human chondrosarcoma cells to berberine. ((a) and (b)) Cells were incubated with various concentrations of berberine for 24 h; p-c-Jun expression was examined by Western blotting. ((c) and (d)) Cells were incubated with various concentrations of berberine for 24 h; AP-1 activity was examined through AP-1 luciferase activity assay. Results are expressed as the mean ± S.E.M.*, compared with control.
