Berberine Reduces the Metastasis of Chondrosarcoma by Modulating the αvβ3 Integrin and the PKCδ, c-Src, and AP-1 Signaling Pathways

<table>Schematic presentation of the signaling pathways involved in berberine-inhibited metastasis of human chondrosarcoma. Berberine inhibits the migration and invasion of human chondrosarcoma cells by modulating the αvβ3 integrin through PKCδ, c-Src, and AP-1 signaling pathway.</table>

Evidence-Based Complementary and Alternative Medicine

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Figure 6

Figure 6: Berberine Reduces the Metastasis of Chondrosarcoma by Modulating the αvβ3 Integrin and the PKCδ, c-Src, and AP-1 Signaling Pathways