Microarray Analysis Reveals the Molecular Basis of Antiarthritic Activity of Huo-Luo-Xiao-Ling Dan
Figure 2
Comparison of the Bhsp65-induced DEG in lymphoid cells of HLXL-treated and Water-treated rats with AA. DEG were categorized into subgroups according to their biological function as follows: (a) general immune activity; (b) antigen processing and presentation; (c) metabolism; (d) other nonimmune related mechanisms involved in arthritis development: adhesion molecule (A), angiogenesis (B), bone damage (C), cellular response to oxygen and oxidation-reduction (D), signal transduction and pathways (E), and autoimmune disease-relevant antigen (F); (e) cell proliferation; (f) chemokines and receptors; (g) cytokines and receptors; and (h) proteins with binding activity (e.g., binding to actin, DNA, etc.). The level of gene expression is presented as fold change above 2, and .
