Microarray Analysis Reveals the Molecular Basis of Antiarthritic Activity of Huo-Luo-Xiao-Ling Dan

Table 1

The gene expression profiles of LNC (ex vivo) of HLXL-/Water-treated rats compared with Untreated rats.

Functional group	Water-treated (Tw)		HLXL-treated (TH)
	Individual-DEG	Shared-DEG		Individual-DEG
Cell proliferation and apoptosis	24	33		3
Immune activity	16	13		3
Metabolism
Lipid metabolism	0	1		1
Oxidation-reduction	0	6		5
Other metabolic processes	5	4		0
Binding activity	14	9		2
Transporter	2	4		2
Signal transduction	2	4		0
Other function	7	5		0
Undefined function	50	47		10
Sub total	120	126		26
Total	246		152

The gene expression profile of Water-treated (T_w) or HLXL-treated (T_H) group versus that of untreated arthritic rats (T₀). Functional category is based on biological processes. DEGs were selected using as cut off fold change >2.0 and 𝑃<0.05 corrected with Benjamin-Hochberg.