Research Article

Destruxin B Isolated from Entomopathogenic Fungus Metarhizium anisopliae Induces Apoptosis via a Bcl-2 Family-Dependent Mitochondrial Pathway in Human Nonsmall Cell Lung Cancer Cells

Figure 6

Schematic representation of destruxin B preparation and mechanistic illustration of destruxin-B-induced apoptosis. Destruxin B isolated from Metarhizium anisopliae induces apoptosis in human nonsmall cell lung cancer cells by activating a mitochondrial-dependent caspase activation signaling pathway.
548929.fig.006