Aconiti Lateralis Preparata Radix Activates the Proliferation of Mouse Bone Marrow Mesenchymal Stem Cells and Induces Osteogenic Lineage Differentiation through the Bone Morphogenetic Protein-2/Smad-Dependent Runx2 Pathway

<table>Immunoblots of p-Smad1/5, p-<i>β</i>-catenin, and total Runx2 after ALR treatment on mBMMSCs. <i>β</i>-tubulin was used as internal control. (a) Immunoblots conducted for the detection of Smad1/5 and p-<i>β</i>-catenin phosphorylation of using extract of mBMMSCs; (b) immunoblots carried out for the detection of Runx2on expression in mBMMSCs extract treated with ALR (100 <i>μ</i>g/mL) or osteogenic induction medium.</table>

Evidence-Based Complementary and Alternative Medicine

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Figure 6

Figure 6: Aconiti Lateralis Preparata Radix Activates the Proliferation of Mouse Bone Marrow Mesenchymal Stem Cells and Induces Osteogenic Lineage Differentiation through the Bone Morphogenetic Protein-2/Smad-Dependent Runx2 Pathway 

Figure 6 | Aconiti Lateralis Preparata Radix Activates the Proliferation of Mouse Bone Marrow Mesenchymal Stem Cells and Induces Osteogenic Lineage Differentiation through the Bone Morphogenetic Protein-2/Smad-Dependent Runx2 Pathway 