Decrease of Obesity by Allantoin via Imidazoline I1-Receptor Activation in High Fat Diet-Fed Mice
Figure 1
The inhibitory effect of I1R antagonist—efaroxan on the allantoin-induced decrease in body weight in HFD-fed mice. Efaroxan (1.5 mg/kg) was intraperitoneally injected 30 min before the injection of allantoin (5 mg/kg). The values are expressed as the mean ± SEM from each group of eight animals compared with the normal chow-fed group at the same time point; compared with the HFD-fed group at the same time point.
