Coniferyl Ferulate, a Strong Inhibitor of Glutathione S-Transferase Isolated from Radix Angelicae sinensis, Reverses Multidrug Resistance and Downregulates P-Glycoprotein

Table 1

The inhibitory effect of CF and positive control EA on the proliferation of B-MD-C1 and multidrug-resistant B-MD-C1 (ADR+/+) cells (𝑋±SD, 𝑛=3, 48 h).

CF (𝜇M)	Inhibitory rate (%)		EA (𝜇M)	Inhibitory rate (%)
	B-MD-C1	B-MD-C1 (ADR +/+)		B-MD-C1	B-MD-C1 (ADR+/+)
3000	27.39±4.70	22.67±7.49	200	99.29±5.68	99.89±7.76
1000	18.62±2.87	10.72±3.21	100	99.52±7.49	94.68±10.23
333.33	5.07±0.20	6.33±0.35	80	78.72±4.53	85.56±5.62
111.11	5.30±1.45	5.42±2.20	60	53.30±6.40	45.61±4.43
37.04	2.56±0.51	3.86±0.49	40	6.56±0.89	5.09±1.35
12.35	1.36±0.41	2.56±0.27	20	4.01±1.18	2.14±1.28
4.12	1.02±0.35	2.11±0.45	10	3.02±0.86	1.34±0.57