Antidepressive-Like Property of Dichloromethane Fraction of Pimenta pseudocaryophyllus and Relevance of Monoamine Metabolic Enzymes

Figure 4

The effect of dichloromethane fraction (DF), imipramine (IMI), or vehicle administration on the immobility after pretreatment with (a) PCPA 100 mg/kg; (b) AMPT 100 mg/kg in FS. Data are presented as mean of immobility time in seconds ± S.E.M. (𝑛=10±2). All differences from the control group are considered to be significant at 𝑃<0.05 or 𝑃<0.01 as denoted by * or **, respectively, while # (𝑃<0.05) or ### (0.001) represents reversion of anti-immobility effect by PCPA or AMPT pretreatments. Except for control group, lack of symbol * or # on the bar indicates 𝑃>0.05.

(a)

(b)