Erectogenic and Aphrodisiac Effects of Butea frondosa Koenig ex Roxb. in Rats: Involvement of Enzyme Inhibition

Figure 4

Masson’s trichrome staining showing smooth muscle (pink) and collagen (blue) level in CCSM of rat at a magnification of 200x. MEBF treatment increased smooth muscle level in CCSM of young rats, and the effect was better than that of sildenafil. Smooth muscle level decreased in aged rat CCSM, and both MEBF and sildenafil treatment increased smooth muscle level significantly, with the effect of MEBF being more pronounced. Picrosirius red staining showing collagen-III (green) and collagen-I (red orange/yellow) level in CCSM of rat at a magnification of 100x. Collagen-III level was more prominent in CCSM of aged rats in comparison to young rats. Treatment of MEBF and sildenafil decreased collagen-III level.