Andrographis paniculata Extract and Andrographolide Modulate the Hepatic Drug Metabolism System and Plasma Tolbutamide Concentrations in Rats
Figure 1
HPLC chromatograms of the andrographolide (1) and 14-deoxy-11,12-didehydroandrographolide (2) standards (1 μg/mL) (a) and the ethanolic extract of Andrographis paniculata (APE; 10 μg/mL) (b). Contents of andrographolide (1) and 14-deoxy-11,12-didehydroandrographolide (2) in APE are 53.2 and 30.6 mg/g, respectively.