Andrographis paniculata Extract and Andrographolide Modulate the Hepatic Drug Metabolism System and Plasma Tolbutamide Concentrations in Rats
Figure 5
DNA-binding activity of nuclear pregnane X receptor (PXR) (a) and aryl hydrocarbon receptor (AhR) (b). Rats were orally administered methyl cellulose (Con), ethanolic extract of Andrographis paniculata (APE), or andrographolide (AND) for 5 days. Nuclear protein extraction and EMSA were performed as described in Section 2. Results of three rats in each group are shown.
