Research Article

Andrographis paniculata Extract and Andrographolide Modulate the Hepatic Drug Metabolism System and Plasma Tolbutamide Concentrations in Rats

Figure 6

Induction by ethanolic extract of Andrographis paniculata (APE) and andrographolide (AND) of hepatic CYP2C6 and CYP2C11 protein expression in high-fat diet-induced obese mice. The animals were orally administered methyl cellulose (Con), 2 g/kg of APE, or 50 mg/kg of AND daily for 5 days. Protein levels in pooled liver samples ( –8) are shown.
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