<i>Persea declinata</i> (Bl.) Kosterm Bark Crude Extract Induces Apoptosis in MCF-7 Cells via  <b>G<sub>0</sub>/G<sub>1</sub></b> Cell Cycle Arrest, Bcl-2/Bax/Bcl-xl Signaling Pathways, and ROS Generation

<table>(a) Acridine orange DNA fragmentation analysis. The cells were treated with DMEM or PDM for 24 h and stained with acridine orange dye. (b) Representative bar charts that show dose-dependent increased fluorescent intensity of acridine orange dye inside the nucleus of the PDM-treated MCF-7 cells, indicating DNA fragmentation.</table>

Evidence-Based Complementary and Alternative Medicine

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Figure 6

Figure 6: <i>Persea declinata</i> (Bl.) Kosterm Bark Crude Extract Induces Apoptosis in MCF-7 Cells via  <b>G<sub>0</sub>/G<sub>1</sub></b> Cell Cycle Arrest, Bcl-2/Bax/Bcl-xl Signaling Pathways, and ROS Generation 

Figure 6 | Persea declinata (Bl.) Kosterm Bark Crude Extract Induces Apoptosis in MCF-7 Cells via  G0/G1 Cell Cycle Arrest, Bcl-2/Bax/Bcl-xl Signaling Pathways, and ROS Generation 