Mechanisms Underlying the Antinociceptive, Antiedematogenic, and Anti-Inflammatory Activity of the Main Flavonoid from Kalanchoe pinnata

Figure 2

Effect of KPFE, KP fractions (a) and KPFV (b) in the carrageenan-induced pleurisy. KPFE, KP fractions (EtOAcF and BuOHF), KPFV, or dexamethasone (Dexa) was subcutaneously administrated 30 min before carrageenan injection (1%, 0.1 mL/10 g). After four hours, the pleural exudate was collected and the total number of leukocytes was counted in a Neubauer chamber. , , and significantly different from the vehicle-treated group. Values represent the mean ± SEM of 8 mice.

(a)

(b)