Supplementation with the Extract of Schisandrae Fructus Pulp, Seed, or Their Combination Influences the Metabolism of Lipids and Glucose in Mice Fed with Normal and Hypercholesterolemic Diet
Table 2
Effects of EtSF supplementation on body weight and food/drug intake in normal and HCL mice.
Groups
Drug concentration (%, w/w)
Body weight (g) in D 1
Body weight (g) in D 10
Food intake (g/kg/day)
Drug intake (g/kg/day)
ND-fed mice
ND
—
18.55 ± 0.09
28.70 ± 0.53
148.54
—
ND/EtSF-S
1
18.58 ± 0.09
28.10 ± 0.45
147.80
1.48
9
18.56 ± 0.09
28.24 ± 0.53
151.48
13.63
ND/FF
0.1
18.52 ± 0.11
26.36 ± 0.65*
145.27
0.15
ND
—
18.14 ± 0.18
28.02 ± 0.45
158.60
—
ND/EtSF-P
1
18.08 ± 0.18
26.55 ± 0.52*
147.39
1.47
9
18.03 ± 0.19
26.38 ± 0.41*
165.29
14.88
ND
18.52 ± 0.10
28.02 ± 0.51
154.29
—
ND/EtSF-S/P
1
18.48 ± 0.11
27.87 ± 0.50
146.88
1.47
9
18.55 ± 0.11
28.42 ± 0.45
145.30
13.08
HCLD-fed mice
ND
—
18.60 ± 0.16
28.48 ± 0.50
156.21
—
HCLD
—
18.68 ± 0.18
28.48 ± 0.49
143.35
—
HCLD/EtSF-S
1
18.55 ± 0.17
29.49 ± 0.53
145.75
1.46
3
18.65 ± 0.16
28.48 ± 0.72
141.09
4.23
9
18.62 ± 0.17
28.07 ± 0.47
141.31
12.72
HCLD/FF
0.1
18.67 ± 0.19
23.81 ± 0.62††
132.00
0.13
ND
—
18.14 ± 0.18
28.02 ± 0.45
158.60
—
HCLD
—
18.63 ± 0.22
27.74 ± 0.59
159.60
—
HCLD/EtSF-P
1
18.92 ± 0.34
28.17 ± 0.62
164.80
1.65
3
18.45 ± 0.25
28.55 ± 0.79
182.16
5.47
9
18.41 ± 0.29
27.06 ± 0.45
171.46
15.43
ND
—
18.52 ± 0.10
28.02 ± 0.51
154.29
—
HCLD
—
19.00 ± 0.26
27.37 ± 0.48
157.86
—
HCLD/EtSF-S/P
1
18.88 ± 0.24
29.04 ± 0.92
167.58
1.68
3
19.14 ± 0.30
28.17 ± 0.47
172.16
5.17
9
18.90 ± 0.30
27.47 ± 0.42
166.41
14.98
Experimental details were described in Table 1. The dosages (g/kg/day) based on crude herbal material were determined with the amount of ingested diet (g/kg/day) and drug concentrations in the diet. Values given are the means ± SEM, with . versus mice fed with ND; versus mice fed with HCLD. Statistical significant differences were determined using a one-way ANOVA followed by Dunnett’s multiple comparisons test or post hoc analysis.
