Research Article

Protective Effect of Flos Lonicerae against Experimental Gastric Ulcers in Rats: Mechanisms of Antioxidant and Anti-Inflammatory Action

Table 2

Antioxidant properties of GC-7101 for HCl/EtOH-induced gastric ulcers.

GroupMDA (nmol/mg protein)GSH/GSSG ratioSOD (U/g protein)Catalase (μmol/min/mg protein)

Vehicle-treated control 0.4 ± 0.118.7 ± 1.097.0 ± 0.122.0 ± 2.1
HCl/EtOH
 Vehicle1.4 ± 0.212.0 ± 0.765.6 ± 0.311.9 ± 1.3
 GC-7101 50 mg/kg0.8 ±0.2+21.1 ± 3.1++102.0 ± 12.8+18.9 ± 2.1+

The values are represented as means ± SEM for eight rats per group. Significantly different (P < 0.05, P < 0.01) from vehicle-treated control group. +,++Significantly different (P < 0.05, P < 0.01) from vehicle-treated HCl/EtOH group.