Xiao Yao San Improves Depressive-Like Behaviors in Rats with Chronic Immobilization Stress through Modulation of Locus Coeruleus-Norepinephrine System

Figure 4

Effect of XYS on the expressions of TH, DBH, and CRF in LC of rats with CIS. ((a), (b), and (c)) The number of positive cells and mean density (SD) of TH, DBH, and CRF in LC of rats were determined by immunohistochemical staining. Data are expressed as mean ± SD, per group. , versus control, ^△ versus model. (d) The protein expressions of TH, DBH and CRF in LC of rats were measured by Western blotting. Data were expressed as mean ± SD, per group. versus control, ^△, ^△△ versus model.

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