Effect of Eclipta prostrata on 11Beta-Hydroxysteroid Dehydrogenase in Rat Liver and Kidney

Table 2

Effects of Eclipta prostrata (7 g/kg, 14 g/kg, and 28 g/kg) on the metabolism of prednisone and prednisolone (1 mg/mL) in rat liver and kidney microsomes (𝑛=6).

Treatment	Activities of enzymes (pmol/min per mg protein)
	11β-HSD I (liver microsomes)	11β-HSD II (kidney microsomes)
Control	383.8±9.0	22.6±2.7
Eclipta prostrata (g/kg)
7	418.2±18.9	29.0±5.1
14	510.1±33.9^∗	36.5±7.6^∗
28	457.2±14.1^∗	29.7±3.6^∗

^∗𝑃<0.05 versus control. Data are mean ± SD.