Gene Expression Profile of Increased Heart Rate in Shensongyangxin-Treated Bradycardia Rabbits

Figure 2

Altered expressed genes in model versus SSYX treatment group and SSYX treatment versus model group. (a) Hierarchical clustering of differentially expressed genes by cluster. Gene expression profiles of SSYX effect on pathological rabbits were executed according to a 2-fold change cutoff. A total of 846 genes deregulated, among which 535 were downregulated and 311 were upregulated. (b) A list of altered genes of interest involved in calcium homeostasis, ion channel, and signaling.

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